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Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
Published on: August 7, 2018
[Necrotizing fasciitis - a clinical diagnosis]
1Klinik für Orthopädie und Unfallchirurgie, Evangelisches Krankenhaus Essen-Werden und Universitätsklinikum Essen, Hufelandstraße 55, 45147, Essen, Deutschland.
Abstract:
Necrotizing fasciitis is a life-threatening clinical pattern, which may lead to multi-organ failure and death with delayed diagnosis or inadequate treatment. We report on a 68-year old patient who developed necrotizing fasciitis of the right elbow with multiorgan failure and long-term ventilation after an accidental and minor injury. The patient survived as a result of an early diagnosis and surgical intervention. In this case report we want to clarify the diagnosis and treatment of necrotizing fasciitis and give an overview of the recent literature on the topic.
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