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The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
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Updated: Mar 16, 2026

Microfluidics in Assessing Platelet Function
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Platelet function testing in cardiac surgery.

S Agarwal1

  • 1Department of Anaesthesia and Critical Care, Liverpool Heart and Chest Hospital, Liverpool, UK. Seema.Agarwal@lhch.nhs.uk.

Transfusion Medicine (Oxford, England)
|August 19, 2016
PubMed
Summary
This summary is machine-generated.

Point-of-care platelet function tests can assess platelet reactivity in patients undergoing cardiac surgery. This review examines devices and their impact on reducing blood loss and improving patient outcomes.

Keywords:
bleedingcardiac surgeryplatelet function

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Area of Science:

  • Cardiology
  • Hematology
  • Surgical Innovation

Background:

  • Bleeding complications in cardiac surgery significantly increase morbidity and mortality.
  • Increased anti-platelet medication use elevates the risk of bleeding in cardiac surgery patients due to platelet dysfunction.
  • Individual variability in platelet inhibition necessitates precise monitoring.

Purpose of the Study:

  • To review point-of-care platelet function testing devices used in cardiac surgery.
  • To evaluate the evidence supporting the use of these devices in assessing platelet reactivity.
  • To determine the effect of these devices on blood loss during cardiac surgery.

Main Methods:

  • Literature review of studies on point-of-care platelet function testing devices.
  • Analysis of evidence regarding device application in cardiac surgery settings.
  • Examination of data correlating device use with patient blood loss.

Main Results:

  • Several point-of-care devices are available for assessing platelet function.
  • Evidence suggests these devices can measure individual platelet reactivity.
  • The impact of these devices on reducing blood loss in cardiac surgery requires further investigation.

Conclusions:

  • Point-of-care testing offers potential for personalized management of platelet function in cardiac surgery.
  • Further research is needed to establish the clinical utility and cost-effectiveness of these devices in reducing blood loss.
  • Optimizing platelet function monitoring may improve patient safety and outcomes in cardiac surgery.