Related Experiment Video

Updated: Mar 16, 2026

Automating Tumor Implantation in Zebrafish Larvae for Cancer Research and Medicine
06:14

Automating Tumor Implantation in Zebrafish Larvae for Cancer Research and Medicine

Published on: September 19, 2025

1.1K

Animal-based studies will be essential for precision medicine

K C Kent Lloyd1, Peter N Robinson1, Calum A MacRae1

  • 1K. C. Kent Lloyd is a professor at the Department of Surgery, School of Medicine, and the Director of the Mouse Biology Program, University of California, Davis, 2795 Second Street, Suite 400, Davis, CA 95618, USA. Email: kclloyd@ucdavis.eduPeter N. Robinson is a professor at Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany, and The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA. Email: peter.robinson@jax.orgCalum A. MacRae is the Chief of cardiovascular medicine at Brigham and Women's Hospital and an associate professor of medicine at Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Science Translational Medicine
|August 19, 2016
PubMed
Summary

No abstract available in PubMed .

More Related Videos

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research09:35

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research

Published on: August 16, 2017

18.4K
A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis07:41

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

3.0K

Related Concept Videos

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
6.7K
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

2.5K
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
6.3K
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
73