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Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
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Anaphylactic reactions presenting with hypertension.
Emrullah Solmazgul1, Ali Kutlu2, Salim Dogru3
1Department of Internal Medicine, GATA Haydarpasa Training Hospital, Istanbul, Turkey.
Springerplus
|August 19, 2016
Summary
Hypertensive anaphylaxis (HA) affects nearly 13% of patients experiencing anaphylaxis. This condition, characterized by high blood pressure during an allergic reaction, can be effectively managed with adrenaline injections.
Area of Science:
- Allergy and Immunology
- Clinical Medicine
Background:
- Limited literature exists on the prevalence of hypertensive anaphylaxis (HA).
- Previous reports on HA are primarily case studies.
- The study aims to determine the prevalence of HA in patients experiencing anaphylaxis.
Purpose of the Study:
- To investigate the prevalence of hypertensive anaphylaxis (HA).
- To review cases of anaphylaxis presenting with concurrent hypertension.
- To establish the incidence of HA in allergic disease diagnostic and treatment procedures.
Main Methods:
- Retrospective review of patient records from January 2010 to December 2014.
- Analysis of patients who experienced anaphylactic reactions post-procedure.
- Inclusion criteria: patients undergoing diagnostic/treatment procedures for allergic diseases.
Main Results:
- Anaphylaxis occurred in 1.43% of 4332 procedures.
- Hypertensive anaphylaxis (HA) was observed in 12.9% of anaphylaxis cases (8 out of 62 patients).
- Two patients with HA received adrenaline injections without adverse effects.
Conclusions:
- Hypertensive anaphylaxis (HA) occurs at a significant rate during anaphylactic reactions.
- Adrenaline injection is an effective treatment for both anaphylaxis and associated hypertension.
- This study represents the first original research on HA prevalence in English medical literature.
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