Related Experiment Video
Updated: Mar 16, 2026

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
Published on: January 17, 2025
Novel Utilization of the Bridge During Weaning Off Venoarterial ECMO: The Hoffman Clamp Method
Sarah E Holgren1, Ryan T Frede, Jennifer P Crumley
1From the *Department of Cardiothoracic Surgery, Divisions of †Respiratory Care and ‡Nursing, University of Iowa Children's Hospital, Iowa City, IA USA; and §Department of Pediatric Cardiology, Children's Hospital Colorado, Aurora, CO USA.
Abstract:
Standard practice for weaning patients off venoarterial extracorporeal membrane oxygenation (ECMO) occurs by decreasing pump flows until idle flow is achieved. This method is limited in its use because it is difficult to assess a patient's true potential to successfully come off ECMO when supported by idle flow. We have developed a weaning technique that uses a Hoffman clamp on the bridge to decrease blood flow to the patient beyond idle flow. This method was used to wean eight patients from venoarterial ECMO. No patients weaned with this technique required emergent reinstitution of ECMO. The Hoffman clamp technique has allowed us to safely wean patients off ECMO support while maintaining integrity of the circuit.
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