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Updated: Mar 16, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
Toxic Alcohol Ingestion: Prompt Recognition And Management In The Emergency Department
Gillian A Beauchamp1, Matthew Valento2
1Adjunct Instructor, Oregon Health & Science University, Department of Emergency Medicine; Toxicology Fellow, Oregon and Alaska Poison Centers, Portland, OR.
Abstract:
Identifying patients with potential toxic alcohol exposure and initiating appropriate management is critical to avoid significant patient morbidity. Sources of toxic alcohol exposure include ethylene glycol, methanol, diethylene glycol, propylene glycol, and isopropanol. Treatment considerations include the antidotes fomepizole and ethanol, and hemodialysis for removal of the parent compound and its toxic metabolites. Additional interventions include adjunctive therapies that may improve acidosis and enhance clearance of the toxic alcohol or metabolites. This issue reviews common sources of alcohol exposure, basic mechanisms of toxicity, physical examination and laboratory findings that may guide rapid assessment and management, and indications for treatment.
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