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Synthesis and antibacterial activity of 5-methylcarbapenems
1Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
The Journal of Antibiotics
|July 1, 1989
Abstract:
Four possible racemic isomers of N-acetyl-5-methylthienamycin derivatives were synthesized and their antibacterial activities are discussed in relation to their physico-chemical properties. 5-Methylcarbapenems having various C-2 side chains were also prepared.