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[Papilledema with visual loss].

K Santirasegaram1, C P Lohmann2, M Ulbig2

  • 1Klinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, München, Deutschland. S.Karthiga@t-online.de.

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PubMed
Summary
This summary is machine-generated.

Acute syphilis can cause papillitis leading to vision loss. This diagnosis requires thorough medical history and diagnostic tests, especially in young men without typical risk factors.

Keywords:
MalesPapilledemaPapillitisSyphilisVisual loss

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Neurology

Background:

  • Papilledema, often associated with increased intracranial pressure, can present with visual disturbances.
  • Syphilis is a complex infectious disease with diverse neurological and ocular manifestations.

Observation:

  • Three male patients presented with unilateral or bilateral visual loss and clinically diagnosed papilledema.
  • Initial neurological and internal medicine examinations were unremarkable.
  • Serological testing confirmed acute syphilis as the underlying cause of suspected papillitis.

Findings:

  • Papillitis with visual loss can be an ocular manifestation of acute syphilis.
  • This presentation mimics other optic neuropathies, including anterior ischemic optic neuropathy (AION).
  • Diagnostic considerations should include syphilis, particularly in young men with visual loss and papilledema without typical AION risk factors.

Implications:

  • Ophthalmologists and neurologists should consider syphilis in the differential diagnosis of papilledema and visual loss, especially in at-risk populations.
  • A comprehensive medical history, including sexual history, and appropriate diagnostic workup are crucial for accurate diagnosis.
  • Early diagnosis and treatment of syphilitic papillitis are essential to prevent permanent vision impairment.