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Updated: Mar 16, 2026

Author Spotlight: Generation of and Comparison Between Patient-Derived Gastric Organoids from Different Regions of the Stomach
Published on: January 26, 2024
Oncogenic Transformation of Human-Derived Gastric Organoids
Nina Bertaux-Skeirik1, Jomaris Centeno2, Jian Gao3
1Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Abstract:
The culture of organoids has represented a significant advancement in the gastrointestinal research field. Previous research studies have described the oncogenic transformation of human intestinal and mouse gastric organoids. Here we detail the protocol for the oncogenic transformation and orthotopic transplantation of human-derived gastric organoids.
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