CREATING AND AUDITING A NEW ELECTRONIC CONTINUOUS INFUSION PRESCRIPTION CHART FOR A PAEDIATRIC CRITICAL CARE UNIT

Emily Siu1, Kalaimaran Sadasivam2, Nanna Christiansen1

  • 1Pharmacy Department, Royal London Hospital, Barts Health NHS Trust.

Insights

An electronic continuous infusion prescription chart significantly reduced pediatric prescription errors, from 30.7% to 0.7%. This tool enhances patient safety in pediatric critical care units by minimizing medication errors.

Area of Science:

  • Pediatric Critical Care Medicine
  • Health Informatics
  • Medication Safety

Background:

  • Prescription errors, particularly for continuous infusions, are a significant concern in pediatric care.
  • Electronic or web-based calculators show promise in minimizing these errors.

Purpose of the Study:

  • To develop and implement an electronic continuous infusion prescription chart in a pediatric critical care unit (PCCU).
  • To audit the chart's effectiveness in reducing prescription errors.

Main Methods:

  • An electronic chart was developed using Excel, incorporating validated formulas for medication calculations based on age and weight.
  • Handwritten prescriptions were audited for 6 months pre-implementation and electronic prescriptions for 6 months post-implementation.
  • Audited parameters included dose, infusion rate, concentration, route, legibility, and patient details.

Main Results:

  • Handwritten prescriptions had a significantly higher error rate (30.7%) compared to electronic charts (0.7%, p<0.002).
  • No errors were detected in electronic prescriptions regarding dose, volume, or rate calculations.
  • The single error on electronic charts was due to incorrect data input.

Conclusions:

  • The electronic continuous infusion prescription chart effectively and significantly reduced prescription error rates in the PCCU.
  • The system offers advantages such as ease of setup, low cost, and adaptability, while improving efficiency of medical and pharmacy resources.
Abstract

Keywords:
AbstractOral

Related Concept Videos

Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
682
Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations01:15

Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations

Gentamicin, an aminoglycoside antibiotic, is commonly administered via intermittent intravenous infusion to treat severe infections. An intermittent one-hour infusion of gentamicin, administered at eight-hour intervals, allows for precise control of plasma drug concentrations, minimizing toxicity while ensuring therapeutic efficacy. Pharmacokinetic principles govern the dynamics of plasma concentrations and can be mathematically described using specific equations.The plasma drug concentration...
307
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
1.6K
IV Infusion to Oral Dosing: Conversion Methods01:28

IV Infusion to Oral Dosing: Conversion Methods

The development of extended-release formulations has facilitated the transition from intravenous to oral medication, offering a more convenient and patient-friendly approach to drug administration. This transition, however, requires careful management to ensure that therapeutic drug levels are maintained, preserving efficacy and avoiding adverse effects. Understanding pharmacokinetic principles and dosage calculations is critical during this process.Pharmacokinetics of the...
124
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
351
One-Compartment Model: IV Infusion01:09

One-Compartment Model: IV Infusion

Intravenous (IV) infusion is often utilized when continuous and controlled drug delivery is necessary, such as during surgery or in the treatment of chronic diseases. This method offers numerous advantages, including immediate drug action, precise control over dosage, and bypassing the first-pass metabolism.
The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
654