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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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Related Experiment Video

Updated: Mar 16, 2026

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
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Normothermic thyroid storm: an unusual presentation.

Anas Ahmad Sabir1, Kabiru Sada2, Bashir O Yusuf3

  • 1Department of Medicine, Usmanu Danfodiyo University Teaching Hospital, PMB 2370 Sokoto, Nigeria.

Therapeutic Advances in Endocrinology and Metabolism
|August 20, 2016
PubMed
Summary
This summary is machine-generated.

Thyroid storm, a severe thyrotoxicosis complication, can present atypically. Clinicians must recognize unusual symptoms like normothermia to ensure timely diagnosis and treatment of this critical condition.

Keywords:
normothermiathyroid stormthyrotoxicosis

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Area of Science:

  • Endocrinology
  • Critical Care Medicine

Background:

  • Thyroid storm is a rare but life-threatening endocrine emergency.
  • It results from severe thyrotoxicosis, often triggered by an underlying stressor.

Purpose of the Study:

  • To highlight the diagnostic challenges posed by atypical presentations of thyroid storm.
  • To emphasize the importance of recognizing normothermia as a potential indicator in thyroid storm cases.

Main Methods:

  • Case report of a 30-year-old female patient presenting with thyrotoxicosis symptoms.
  • Analysis of clinical presentation, focusing on unusual features such as normothermia.

Main Results:

  • The patient exhibited restlessness, tachycardia, and vomiting.
  • Notably, the patient presented with normothermia, an atypical finding for thyroid storm.

Conclusions:

  • Thyroid storm can manifest with unusual clinical features, complicating diagnosis.
  • Increased clinical awareness of atypical presentations, including normothermia, is crucial for prompt management of thyroid storm.