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Transplanted ossicles after two decades.

J Lang1, A G Kerr, G D Smyth

  • 1Royal Victoria Hospital, Belfast.

The Journal of Laryngology and Otology
|May 1, 1989
PubMed
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Histological examination of long-term ossicles reveals their appearance after 20-21 years. This study analyzes autologous and homologous incus specimens from middle ear revision surgery, detailing their tissue structure.

Area of Science:

  • Otolaryngology
  • Histopathology
  • Biomaterials Science

Background:

  • Middle ear ossicles are crucial for hearing.
  • Long-term outcomes of repositioned or implanted ossicles require detailed histological evaluation.
  • Understanding the fate of autologous and homologous incus grafts is important for surgical success.

Purpose of the Study:

  • To histologically examine two very long-term human incus specimens.
  • To assess the tissue changes in autologous and homologous incus grafts after prolonged periods in the middle ear.

Main Methods:

  • Histological analysis of two human incus specimens (autologous and homologous).
  • Specimens were retrieved after 21 and 20 years, respectively.
  • Standard histological techniques including formalin fixation, decalcification (EDTA), paraffin embedding, serial sectioning, and H&E staining were employed.

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Main Results:

  • Detailed histological findings of the two long-term incus specimens are presented.
  • The study provides insights into the tissue preservation and potential changes over two decades.

Conclusions:

  • Histological examination of very long-term ossicles provides valuable data on graft viability and tissue integration.
  • This research contributes to the understanding of the long-term behavior of autologous and homologous incus grafts in the middle ear.