Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

918
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
918
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

1.8K
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canonical and variant histones of protozoan parasites.

Frontiers in bioscience (Landmark edition)·2011
See all related articles

Related Experiment Video

Updated: Mar 16, 2026

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy
03:14

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy

Published on: January 31, 2025

1.8K

Predicting benefit from lumbar epidural steroid injection: commentary.

William Joseph Sullivan1

  • 1Physical Medicine and Rehabilitation, University of Colorado School of Medicine, 12631 East 17th Ave, AO1, Room 2510, MailStop F-493, Aurora, CO 80045, USA.

The Spine Journal : Official Journal of the North American Spine Society
|August 23, 2016
PubMed
Summary

This commentary reviews predictors of epidural steroid injection efficacy for lumbar degenerative conditions. It highlights factors influencing treatment success in spinal stenosis and disc disease.

More Related Videos

Author Spotlight: Scope of LE-ULBD as a Safe, Effective, and Minimally Invasive Approach to Treat Lumbar Spinal Stenosis
05:17

Author Spotlight: Scope of LE-ULBD as a Safe, Effective, and Minimally Invasive Approach to Treat Lumbar Spinal Stenosis

Published on: February 9, 2024

1.5K
Full-Endoscopic Isolation Zone Technique for the Treatment of Lumbar Disc Herniation
05:42

Full-Endoscopic Isolation Zone Technique for the Treatment of Lumbar Disc Herniation

Published on: April 7, 2023

1.4K

Related Experiment Videos

Last Updated: Mar 16, 2026

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy
03:14

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy

Published on: January 31, 2025

1.8K
Author Spotlight: Scope of LE-ULBD as a Safe, Effective, and Minimally Invasive Approach to Treat Lumbar Spinal Stenosis
05:17

Author Spotlight: Scope of LE-ULBD as a Safe, Effective, and Minimally Invasive Approach to Treat Lumbar Spinal Stenosis

Published on: February 9, 2024

1.5K
Full-Endoscopic Isolation Zone Technique for the Treatment of Lumbar Disc Herniation
05:42

Full-Endoscopic Isolation Zone Technique for the Treatment of Lumbar Disc Herniation

Published on: April 7, 2023

1.4K

Area of Science:

  • Neurosurgery
  • Orthopedic Surgery
  • Pain Management

Background:

  • Epidural steroid injections (ESIs) are a common treatment for lumbar degenerative pathology.
  • Predicting the efficacy of ESIs remains a challenge in clinical practice.
  • Understanding predictors can optimize patient selection and treatment outcomes.

Purpose of the Study:

  • To analyze the key predictors of successful epidural steroid injections.
  • To evaluate factors influencing pain relief and functional improvement in patients with lumbar degenerative conditions.
  • To provide insights for clinicians regarding ESI effectiveness.

Main Methods:

  • This is a commentary analyzing a previously published study.
  • The commentary critically evaluates the methodology and findings of the referenced study.
  • It synthesizes existing knowledge on predictors of ESI efficacy.

Main Results:

  • The efficacy of ESIs is influenced by various patient-related and pathology-specific factors.
  • Factors such as the type of degenerative pathology and baseline pain severity are important.
  • The commentary discusses the limitations in predicting ESI outcomes.

Conclusions:

  • Accurate prediction of epidural steroid injection efficacy requires consideration of multiple factors.
  • Further research is needed to refine predictive models for lumbar degenerative conditions.
  • Optimizing ESI use involves careful patient selection based on identified predictors.