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Related Concept Videos

Common Respiratory Disorders01:31

Common Respiratory Disorders

1.7K
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
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Other Pulmonary Disorders01:17

Other Pulmonary Disorders

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Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

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Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
1.4K
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

111
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
111
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Updated: Mar 16, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

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Respiratory Allergic Disorders.

Jason Raymond Woloski1, Skye Heston1, Sheyla Pamela Escobedo Calderon2

  • 1Department of Family Medicine, Penn State Hershey Medical Center, 500 University Drive, H154, PO Box 850, Hershey, PA 17033-0850, USA.

Primary Care
|August 23, 2016
PubMed
Summary
This summary is machine-generated.

Allergic asthma involves airway inflammation triggered by allergens. Allergic bronchopulmonary aspergillosis is a fungal hypersensitivity reaction complicating asthma and cystic fibrosis.

Keywords:
AllergicAllergic bronchopulmonary aspergillosisAsthmaHypersensitivity pneumonitis

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Area of Science:

  • Pulmonology
  • Allergy and Immunology
  • Infectious Diseases

Background:

  • Allergic asthma is a chronic condition characterized by reversible bronchoconstriction due to allergic triggers, presenting with cough, wheezing, and shortness of breath.
  • Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity reaction often seen in asthma or cystic fibrosis patients, caused by Aspergillus species colonizing the bronchi.
  • Hypersensitivity pneumonitis involves lung inflammation from inhaling airborne antigens like molds and dust.

Purpose of the Study:

  • To differentiate between allergic asthma, allergic bronchopulmonary aspergillosis, and hypersensitivity pneumonitis.
  • To highlight the distinct clinical presentations and etiological factors of these related respiratory conditions.
  • To inform diagnostic and therapeutic strategies for patients with complex allergic airway diseases.

Main Methods:

  • Review of clinical manifestations and diagnostic criteria for allergic asthma, ABPA, and hypersensitivity pneumonitis.
  • Analysis of etiological agents, including common allergens and fungal species.
  • Comparison of key symptoms such as bronchoconstriction, mucus production, eosinophilia, and inflammatory responses.

Main Results:

  • Allergic asthma is defined by reversible bronchoconstriction and allergic triggers.
  • ABPA presents as asthma complicated by bronchial obstruction, fever, malaise, and eosinophilia due to Aspergillus.
  • Hypersensitivity pneumonitis results from inhaled antigens causing lung inflammation.

Conclusions:

  • Accurate differentiation between these conditions is crucial for effective management.
  • Understanding the specific triggers and immune responses is key to treating allergic airway diseases.
  • Early diagnosis and targeted therapy can improve outcomes for patients with asthma and related lung conditions.