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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
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Recirculation in venovenous extracorporeal membrane oxygenation
Ashleigh Xie1, Tristan D Yan2, Paul Forrest3
1The Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia.
Journal of Critical Care
|August 23, 2016
Summary
Recirculation is a common complication of venovenous extracorporeal membrane oxygenation (ECMO) that can cause hypoxemia. This review highlights current measurement methods and suggests further research is needed for optimal management and cannula strategies.
Area of Science:
- Cardiovascular Medicine
- Respiratory Medicine
- Medical Technology
Background:
- Venovenous extracorporeal membrane oxygenation (ECMO) is increasingly used for severe respiratory failure.
- Recirculation is a frequent complication, potentially leading to hypoxemia and organ damage.
Purpose of the Study:
- To review current evidence on the causes, measurement, and management of recirculation during ECMO.
- To identify gaps in knowledge and areas for future research.
Main Methods:
- Systematic review of 38 studies from six electronic databases (inception to January 2016).
- Analysis focused on recirculation causes, measurement techniques, and management strategies.
Main Results:
- Recirculation is typically measured using blood oxygen saturations; oxygen content may be more accurate.
- Dilutional ultrasound shows promise for monitoring but requires further validation.
- Cannula configuration and ECMO flow rate influence recirculation, but optimal techniques are not established.
- Dual-lumen cannulas may reduce recirculation if correctly positioned.
Conclusions:
- Further clinical and laboratory studies are essential to better understand and manage ECMO recirculation.
- Optimizing cannula selection and positioning is crucial for minimizing recirculation.
- Accurate measurement and effective management strategies are needed to improve patient outcomes.
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