Related Experiment Video
Updated: Mar 16, 2026

04:14
Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults
Published on: February 28, 2025
988
Harmonic Scalpel versus Monopolar Electrocauterization in Cholecystectomy
Guanqun Liao1, Shunqian Wen1, Xueyi Xie1
1Department of General Surgery, Foshan Municipal Hospital, Southern Medical University, Foshan, China.
JSLS : Journal of the Society of Laparoendoscopic Surgeons
|August 23, 2016
Summary
Laparoscopic cholecystectomy (LC) with the Harmonic scalpel is as effective and safe as traditional electrocautery for gallstone and gallbladder inflammation treatment. Both methods show comparable outcomes in operative time, blood loss, and recovery.
Area of Science:
- Surgical Innovation
- Gastrointestinal Surgery
- Minimally Invasive Procedures
Background:
- Laparoscopic cholecystectomy (LC) using electrocautery is standard for gallstones and gallbladder inflammation.
- The Harmonic scalpel offers potential benefits like reduced thermal damage in LC.
Purpose of the Study:
- To compare the effectiveness and safety of the Harmonic scalpel versus electrocautery in LC.
- To evaluate operative time, blood loss, conversion rates, hospital stay, pain, and cost-effectiveness.
Main Methods:
- 198 patients undergoing LC were randomized to Harmonic scalpel (117) or electrocautery (81).
- Data collected included operative time, blood loss, conversion to laparotomy, hospital stay, pain, and cost.
Main Results:
- No significant differences were observed between the Harmonic scalpel and electrocautery groups.
- Operative time, bleeding, conversion rates, and recovery duration were comparable (P > .05).
Conclusions:
- Conventional monopolar electrocautery is equally effective and safe as the Harmonic scalpel for LC.
- Both techniques are suitable for treating uncomplicated cholecystitis and cholelithiasis.

