Antithrombin Supplementation and Mortality in Sepsis-Induced Disseminated Intravascular Coagulation: A Multicenter...

Mineji Hayakawa¹, Daisuke Kudo, Shinjiro Saito+43

• ¹*Emergency and Critical Care Center, Hokkaido University Hospital, Sapporo, Japan †Division of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan ‡Intensive Care Unit, Department of Anesthesiology, Jikei University School of Medicine, Tokyo, Japan §Department of Emergency Medicine, Osaka General Medical Center, Osaka, Japan ||Department of Anesthesiology and Critical Care Medicine, Jichi Medical University Saitama Medical Center, Saitama, Japan ¶Department of Critical Care, Shonan Kamakura General Hospital, Kamakura, Japan #Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Suita, Japan **Department of Emergency Medicine, University of Occupational and Environmental Health, Kita-Kyushu, Japan ††Clinical Research and Medical Innovation Center, Hokkaido University Hospital, Sapporo, Japan ‡‡Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Tokyo, Japan §§Department of Emergency and Critical Care Medicine, Ohta General Hospital Foundation, Ohta Nishinouchi Hospital, Koriyama, Japan ||||Pharmaceutical Department, JA Hiroshima General Hospital, Hiroshima, Japan ¶¶Department of Emergency and Critical Care Medicine, Saitama Red Cross Hospital, Saitama, Japan ##Department of Emergency and Critical Care Medicine, Wakayama Medical University, Wakayama, Japan ***Department of Emergency Medicine and Critical Care Medicine, Advanced Medical Emergency Department and Critical Care Center, Japan Red Cross Maebashi Hospital, Maebashi, Japan †††Emergency and Critical Care Center, Kyushu University Hospital, Fukuoka, Japan ‡‡‡Department of Emergency and Critical Care Medicine, Fukuoka University Hospital, Fukuoka, Japan §§§Emergency Department, Ibaraki Prefectural Central Hospital, Kasama, Japan ||||||Division of Intensive Care, Nagasaki University Hospital, Nagasaki, Japan ¶¶¶Department of Emergency and Critical Care Medicine, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan ###Anesthesiology, Kyoto First Red-Cross Hospital, Kyoto, Japan ****Intensive Care Unit, Saiseikai Yokohamasi Tobu Hospital, Yokohama, Japan ††††Department of Emergency Medicine, Asahikawa Medical University, Asahikawa, Japan ‡‡‡‡Shock and Trauma Center, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Japan §§§§Emergency Medicine, Kameda Medical Center, Kamogawa, Japan ||||||||Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Japan ¶¶¶¶Emergency and Critical Care Medicine, Asahikawa Red Cross Hospital, Asahikawa, Japan ####Department of Emergency and Critical Care Medicine, Graduate School of Medicine, University of the Ryukyus, Nishihara, Japan *****Advanced Critical Care Center, Gifu University Hospital, Gifu, Japan †††††Emergency and Critical Care Center, Saga University Hospital, Saga, Japan ‡‡‡‡‡The Division of Cardiovascular Disease, Steel Memorial Muroran Hospital, Muroran, Japan §§§§§Department of Emergency Medicine and Critical Care, Sapporo City General Hospital, Sapporo, Japan ||||||||||Division of Emergency Medicine, Ehime University Hospital, Matsuyama, Japan ¶¶¶¶¶Intensive Care Unit, Tomishiro Central Hospital, Tomishiro, Japan #####Department of Emergency Medicine, Akashi City Hospital, Akashi, Japan ******Critical Care Department, Sendai City Hospital, Sendai, Japan ††††††Emergency Department, Hakodate Municipal Hospital, Hakodate, Japan ‡‡‡‡‡‡Emergency and Critical Care Center, Mie University Hospital, Tsu, Japan §§§§§§Department of Emergency Medicine, Gunma University, Maebashi, Japan ||||||||||||Department of Anesthesia and Intensive Care, KKR Sapporo Medical Center, Sapporo, Japan ¶¶¶¶¶¶Emergency and Critical Care Center, Seirei Mikatahara General Hospital, Hamamatsu, Japan ######Intensive Care Unit, Hyogo College of Medicine, Nishinomiya, Japan.