Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

199
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
199
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

311
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
311
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

329
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
329
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors01:20

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors

1.5K
Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
1.5K
Urinary Tract Calculi V: Nursing Management01:28

Urinary Tract Calculi V: Nursing Management

396
AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
396
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

594
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
594

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Validation of the PEN-FAST Penicillin Allergy Clinical Decision Rule in an Asian Cohort.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2025
Same author

Understanding the uncommon: Insights into thymoma associated immunodeficiency.

Asian Pacific journal of allergy and immunology·2025
Same author

Montreal cognitive assessment as a screening instrument for cognitive impairment in systemic lupus erythematosus patients without overt neuropsychiatric manifestations.

Lupus·2022
Same author

Lessons Learnt from the COVID-19 Pandemic: Starting Residency in a Foster Institution.

Journal of medical education and curricular development·2021
Same author

Psychological impact of the COVID-19 pandemic on training of postgraduate year 1 doctors in Singapore.

Singapore medical journal·2021
Same author

Perceived Stress, Stigma, Traumatic Stress Levels and Coping Responses amongst Residents in Training across Multiple Specialties during COVID-19 Pandemic-A Longitudinal Study.

International journal of environmental research and public health·2020

Related Experiment Video

Updated: Mar 16, 2026

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
07:22

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

1.1K

Poorly controlled gout: who is doing poorly?

Faith Li-Ann Chia

    Singapore Medical Journal
    |August 24, 2016
    PubMed
    Summary

    Gout management faces challenges due to patient and physician factors hindering treatment adherence and effectiveness. Bridging this gap requires enhanced education and guideline implementation for better patient outcomes.

    Area of Science:

    • Rheumatology
    • Inflammatory Arthritis
    • Crystal Arthropathies

    Background:

    • Gout, characterized by monosodium urate crystal deposition, is a prevalent inflammatory arthritis.
    • Recent advances in therapy and pathophysiology have renewed interest in gout management.
    • A significant gap persists between established treatment goals and clinical practice.

    Purpose of the Study:

    • To identify barriers to effective gout management in clinical practice.
    • To highlight the need for improved physician and patient education.
    • To emphasize the importance of guideline dissemination and adherence.

    Main Methods:

    • Review of current literature on gout pathophysiology and treatment.
    • Analysis of patient-related factors (understanding, stigma, adherence).
    Keywords:
    allopurinoldrug hypersensitivityhyperuricaemiamedication adherence

    Related Experiment Videos

    Last Updated: Mar 16, 2026

    Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
    07:22

    Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

    Published on: March 7, 2025

    1.1K
  • Analysis of physician-related factors (knowledge, allopurinol use, ownership).

    • Main Results:

    • Poorly controlled gout results from patient factors like poor disease understanding and nonadherence.
    • Physician factors, including knowledge gaps and suboptimal allopurinol use, contribute to treatment failures.
    • Existing international guidelines are not fully integrated into daily practice.

    Conclusions:

    • Addressing patient and physician barriers is crucial for improving gout control.
    • Enhanced education, clear treatment targets, and appropriate pharmacotherapy are essential.
    • Dissemination and implementation of gout management guidelines are necessary to bridge the practice gap.