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Effects of Blood Pressure Control in Cardiovascular Prevention
Nathan Artom1, Alessandra Vecchie, Aldo Pende
1Department of Internal Medicine, University of Genoa School of Medicine. IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, 6 viale Benedetto XV, 16100 Genoa, Italy.
Insights
Uncontrolled high blood pressure is a growing global health issue. This review explores strategies to improve blood pressure control and reduce cardiovascular events in hypertensive patients.
Area of Science:
- Cardiology
- Public Health
Background:
- High blood pressure (hypertension) is a leading global cause of mortality and morbidity.
- There has been a concerning increase in uncontrolled hypertension cases in recent decades.
Purpose of the Study:
- To review the diagnosis, pathophysiology, and clinical consequences of arterial hypertension.
- To identify factors crucial for effective blood pressure control.
- To explore strategies for reducing uncontrolled hypertension and associated cardiovascular events.
Main Methods:
- A narrative review of literature sourced from MEDLINE and PubMed up to June 2016.
- Search terms included "hypertension, blood pressure control" combined with "pathophysiology, lifestyle, antihypertensive drugs, target organ damage, target values and comorbidity".
Main Results:
- Achieving adequate blood pressure control presents a significant challenge at both population and individual levels.
- The review focuses on factors contributing to and maintaining uncontrolled hypertension.
Conclusions:
- The review discusses optimal strategies to decrease uncontrolled hypertension and cardiovascular events.
- It highlights new approaches for enhanced blood pressure management, incorporating recent clinical trial data.
Background:
High blood pressure is the main risk factor worldwide for mortality and morbidity. Subjects with uncontrolled hypertension increased in the last decades.
Methods:
This review is based on the material searched for and obtained via MEDLINE and PubMed up to June 2016. The search terms used were "hypertension, blood pressure control" in combination with "pathophysiology, lifestyle, antihypertensive drugs, target organ damage, target values and comorbidity".
Results:
This narrative review focused its attention on the diagnosis, the pathophysiology, the clinical consequences of arterial hypertension, and on the factors that must be considered for a better blood pressure control. In fact, the attainment of an adequate blood pressure control is a challenge at both a population and an individual level.
Conclusion:
The review will discuss the best strategy to reduce uncontrolled hypertension and cardiovascular events in hypertensive patients identifying the main conditions which determine and maintain uncontrolled hypertension also highlighting the new possible strategies for a better blood pressure control and including the results of very recent multicenter randomized controlled trials.
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