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Updated: Mar 16, 2026
Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
Published on: May 3, 2018
Arterial stiffness in children with and without probable developmental coordination disorder
Nicole E Philips1, Daniele Chirico1, John Cairney2
1Faculty of Applied Health Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Insights
Males with probable developmental coordination disorder (p-DCD) exhibit increased arterial stiffness and pulse wave velocity, linked to higher body fat. Early interventions are crucial for these children to mitigate future cardiovascular risks.
Area of Science:
- Pediatric cardiovascular health
- Developmental coordination disorder research
- Arterial physiology
Background:
- Children with cardiovascular disease risk factors show arterial changes predicting adult morbidity.
- Children with developmental coordination disorder (DCD) face elevated cardiovascular risk due to obesity and inactivity.
Purpose of the Study:
- To evaluate arterial structure and function in children with and without probable DCD (p-DCD).
Main Methods:
- Cross-sectional study of 33 children with p-DCD and 53 controls.
- Movement Assessment Battery for Children used for p-DCD classification.
- BOD POD for adiposity assessment; common carotid artery (CCA) compliance, distensibility, and intima-media thickness measured.
- ECG R-wave-to-toe pulse wave velocity (PWV) assessed.
Main Results:
- Males with p-DCD had significantly lower CCA distensibility and higher PWV compared to controls.
- No significant arterial differences were observed in females with p-DCD.
- Body fat percentage predicted CCA distensibility and mediated the effect of p-DCD on PWV in males.
Conclusions:
- Males with p-DCD demonstrate increased arterial stiffness, likely due to higher body fat.
- Findings highlight the need for targeted interventions in males with p-DCD to prevent future cardiovascular disease.
Background:
Children with cardiovascular disease risk factors demonstrate adverse arterial alterations that are predictive of cardiovascular morbidity and mortality in adults. Children with developmental coordination disorder (DCD) are at cardiovascular risk as they are more likely to be obese and inactive.
Aim:
The purpose of this study was to assess arterial structure and function in children with and without probable DCD (p-DCD).
Methods:
A cross-sectional study of 33 children with p-DCD (22 male) and 53 without (30 male). The Movement Assessment Battery for Children was used to classify those with p-DCD. Adiposity was assessed using the BOD POD. Compliance, distensibility, and intima-media thickness were measured at the common carotid artery (CCA). ECG R-wave-to-toe pulse wave velocity (PWV) was also measured.
Results:
Compared to controls, males with p-DCD had lower CCA distensibility (p=0.034) and higher PWV (p=0.001). No differences were evident in females. Body fat percent was a significant predictor of CCA distensibility and removed the effect of p-DCD on PWV in males.
Conclusions:
The present study demonstrates augmented arterial stiffness in males with p-DCD, likely attributed to body fat. These findings underscore the importance of targeted interventions in children with p-DCD, specifically males, in order to prevent future cardiovascular risk.
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