Related Experiment Video
Updated: Mar 16, 2026

A DNA/Ki67-Based Flow Cytometry Assay for Cell Cycle Analysis of Antigen-Specific CD8 T Cells in Vaccinated Mice
Published on: January 5, 2021
State-Level Voting Patterns and Adolescent Vaccination Coverage in the United States, 2014
Steven Bernstein1, Anna North1, Jason Schwartz1
1Steven Bernstein is with the Department of Emergency Medicine, Yale Cancer Center, New Haven, CT, and the Robert Wood Johnson Clinical Scholars Program, Yale School of Medicine, New Haven. Linda M. Niccolai and Anna North are with the Department of Epidemiology of Microbial Diseases, Yale School of Public Health and Yale Cancer Center. Jason Schwartz is with the Department of Health Policy and Management, Yale School of Public Health, New Haven.
State voting patterns are linked to adolescent vaccination rates. Blue states, affiliated with Democrats, showed higher coverage for human papillomavirus (HPV), tetanus-containing (Tdap), and meningococcal (MCV4) vaccines compared to red states.
Area of Science:
- Public Health
- Epidemiology
- Political Science
Background:
- Adolescent vaccination is crucial for preventing infectious diseases.
- Understanding factors influencing vaccine uptake is essential for public health strategies.
- State-level political affiliation may correlate with health behaviors and outcomes.
Purpose of the Study:
- To investigate the association between state-level voting patterns and adolescent vaccination coverage.
- To analyze coverage for human papillomavirus (HPV), tetanus-containing (Tdap), and meningococcal (MCV4) vaccines.
- To determine if political affiliation influences vaccination rates in adolescents.
Main Methods:
- States were categorized as 'blue' (Democratic) or 'red' (Republican) based on 2012 Presidential election results.
- Multivariable models were employed to adjust for sociodemographic, healthcare access, and vaccination policy confounders.
- Separate analyses were conducted for HPV vaccination in boys and girls.
Main Results:
- Adolescent vaccination coverage was significantly higher in blue states compared to red states for all examined vaccines (P < .05).
- Adjusted analyses revealed notable differences: 10.2% higher HPV coverage in girls, 24.9% higher in boys, 6.2% higher for Tdap, and 14.1% higher for MCV4 in blue states.
- These findings indicate an independent association between state political affiliation and adolescent vaccine uptake.
Conclusions:
- State-level voting patterns are independently associated with coverage of recommended adolescent vaccines.
- Observed disparities in vaccination coverage between blue and red states may stem from underlying differences in cultural norms and social values.
- Public health interventions aimed at increasing adolescent vaccination coverage should consider the influence of local political contexts.
Related Concept Videos
Vaccinations
Bias in Epidemiological Studies
Contingency Table
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Cognitive Development During Adolescence
Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...

