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Changes in Hematologic and Coagulation Profiles in Rabbits with Right-ventricle Pacing
Ivana Uhrikova1, Milan Sepsi2, Jana Hlozkova3
1Department of Physiology, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic
Objectives:
The aim of this study was to evaluate changes in hematology and coagulation in rabbits with right-ventricle pacing without medication.
Animals And Methods:
Blood was collected from ten non-anesthetized male rabbits from the jugular vein before and one month after pacemaker placement. Total erythrocyte, leukocyte and platelet count, hemoglobin, hematocrit and differential leukocyte count were done on automatic veterinary flow cytometry hematologic analyzer. Prothrombin time, activated partial thromboplastin time, fibrinogen level, D-dimers and kaolin-activated thromboelastography was measured from citrated blood.
Results:
We found an increase in red blood cell mass and decrease in platelet count, while coagulation tests did not diff er between samplings.
Conclusion:
Right-ventricle pacing seems to have no influence on hemostasis in rabbits.
