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Updated: Jul 27, 2026

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
Published on: August 14, 2013
[Late results of transscleral hypotensive low-energy laser therapy of glaucoma]
Abstract:
The paper discusses remote observations (within 5 years) over 64 patients (94 eyes) with open-angle glaucoma after transscleral hypotensive low-energy laser therapy. Before treatment, intraocular pressure was moderately increased in 63 eyes (67%), high--in 31 (33%). In 27 eyes with minimum, moderately expressed dystrophic changes in the anterior segment of the eye, a course of transscleral hypotensive low-energy laser therapy, 1-2 sessions, resulted in normalization of intraocular pressure and improvement of hydrodynamics, remaining stable within the whole period of observation. In 49 eyes with moderately expressed dystrophic changes in the anterior segment of the eye, a course of 3-5 sessions brought about normalization of intraocular pressure, remaining stable within 6-12 months, on the average. In 18 eyes with strongly expressed dystrophic changes in the anterior segment of the eye, a partial hypotensive effect was achieved and the patients were operated a month later. In patients with a normalized intraocular pressure, stabilization of visual functions (visual acuity and visual field) within the whole period of observation is also recorded.
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