Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Depression and heart failure - a dangerous combination].

Sven M Piepenburg, Georg Ertl, Christiane E Angermann

    Deutsche Medizinische Wochenschrift (1946)
    |August 25, 2016
    PubMed
    Summary

    Depression is common in heart failure patients, impacting quality of life and clinical outcomes. While antidepressants show no benefit, therapies like physical training and cognitive behavioral therapy improve symptoms and prognosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Left ventricular non-compaction in heart failure: contemporary perspective on diagnostic challenges and treatment opportunities.

    Heart failure reviews·2026
    Same author

    Empagliflozin in De Novo vs Acute Decompensated Chronic Heart Failure: A Prespecified Analysis From EMPULSE.

    JACC. Heart failure·2026
    Same author

    Comorbidities - Integrating Complexity into Heart Failure Care.

    Current heart failure reports·2025
    Same author

    Global patterns of polypharmacy after acute heart failure hospitalization: Prevalence and outcomes from the REPORT-HF registry.

    European journal of heart failure·2025
    Same author

    Digoxin Reduces Pulmonary Artery Pressure in Patients With Heart Failure: A Report of the CardioMEMS Database.

    JACC. Heart failure·2025
    Same author

    Relationship Between Remote, Ambulatory Pulmonary Artery Pressures, and All-Cause Mortality in Patients With Chronic Heart Failure.

    Circulation. Heart failure·2025

    Area of Science:

    • Cardiology
    • Psychiatry
    • Public Health

    Background:

    • Depression frequently co-occurs with heart failure, significantly diminishing patient quality of life and worsening clinical outcomes.
    • Both heart failure and depression are prevalent conditions with rising incidence and healthcare costs, highlighting their substantial socio-economic impact.
    • Interconnected biological and behavioral factors, including reduced treatment adherence in depressed heart failure patients, and shared genetic predispositions are implicated in their pathophysiology.

    Purpose of the Study:

    • To review the interplay between depression and heart failure.
    • To assess the efficacy of various treatment modalities for comorbid depression in heart failure patients.

    Main Methods:

    • Literature review examining the relationship between depression and heart failure.

    Related Experiment Videos

  • Analysis of evidence regarding treatment outcomes for comorbid depression in heart failure.

    • Main Results:

    • Depression negatively affects heart failure prognosis and quality of life.
    • Antidepressant pharmacotherapy has not demonstrated efficacy in improving depressive symptoms, mortality, or morbidity in heart failure patients.
    • Physical training, cognitive behavioral therapy, and comprehensive disease management have shown promise in improving symptoms and/or prognosis in individual studies.

    Conclusions:

    • Depression is a significant comorbidity in heart failure with considerable clinical and socio-economic relevance.
    • Current evidence does not support antidepressant pharmacotherapy for comorbid depression in heart failure.
    • Non-pharmacological interventions like physical training and CBT offer potential benefits for managing depression in heart failure.