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Updated: Mar 15, 2026

Apparatus for Harvesting Tissue Microcolumns
Published on: October 25, 2018
Minimizing injury to the donor area in follicular unit extraction (FUE) harvesting
Georgios Zontos1,2, Ken L Williams3, George Nikiforidis2
1Haarklinikken, Copenhagen, Denmark.
Background:
Follicular Unit Extraction (FUE) is considered to be a minimally invasive procedure, and the injury to the donor area caused by a sharp punch may result in dermal fibrosis and clinically observed hypopigmentation.
Objective:
To evaluate with advanced image processing the efficacy of using 0.9% normal saline in minimizing the injury to the donor area in FUE donor harvesting.
Patients And Methods:
The term acute extraction (AE) is used to describe the donor harvesting technique, whereby a follicular unit (FU) is removed with a punch that is aligned parallel with the exit angle of the hair follicle. The term vertical extraction (VE) describes the technique where a FU is removed in like manner, but normal saline is injected intradermally prior to harvesting so the punch being perpendicular to the skin. Thirty-five patients were selected for this study to apply both harvesting techniques and then to compare the differences in wound surface size and skin mass removed by the punch.
Results:
A significant reduction in the mean values of wound surface and skin mass was recorded in vertical extraction compared to those in acute extraction.
Conclusion:
The injection of normal saline prior to harvesting proved to be very efficient in minimizing skin injury in FUE harvesting.

