Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epigenetic Regulation01:46

Epigenetic Regulation

34.2K
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
34.2K
Epigenetic Regulation01:46

Epigenetic Regulation

26.2K
26.2K
Epigenetic Regulation01:37

Epigenetic Regulation

4.1K
Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
4.1K
Epistasis Analysis01:09

Epistasis Analysis

6.2K
Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...
6.2K
Histone Modification02:32

Histone Modification

16.9K
The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone...
16.9K
Histone Modification02:32

Histone Modification

4.8K
4.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Selective inhibition of STAT3 transcriptional activity by novel small molecules alleviates the development of lupus in mice.

Translational research : the journal of laboratory and clinical medicine·2026
Same author

Development and Validation of a Korean (L1)-English (L2) Speech Processing Task System for Children with and without Speech Sound Disorders.

Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP)·2026
Same author

Divergence between neural and retinal lineage specification during human brain development by signal transduction.

Journal of advanced research·2025
Same author

# Language processing characteristics in normal pressure hydrocephalus: insights from eye-tracking analysis of incorrect responses.

Frontiers in aging neuroscience·2025
Same author

HELLS controls mitochondrial dynamics and genome stability in liver cancer by collusion with MIEF1.

Cell death & disease·2025
Same author

Exploring Voice Acoustic Features Associated with Cognitive Status in Korean Speakers: A Preliminary Machine Learning Study.

Diagnostics (Basel, Switzerland)·2025

Related Experiment Video

Updated: Mar 15, 2026

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
10:41

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

Published on: April 5, 2018

10.9K

Mapping the Technological Knowledge Landscape: The Case of Epigenetics.

Chie Hoon Song, Janghyeok Yoon, Namuk Ko

  • 1Research Center for Epigenome Regulation, School of Pharmacy, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon 16419, South Korea. jhhan551@skku.edu.

Recent Patents on Anti-Cancer Drug Discovery
|August 26, 2016
PubMed
Summary

Epigenetics research is rapidly advancing, with key trends in histone deacetylase inhibition, DNA methylation, and data mining for health insights. This patent analysis reveals significant growth and potential for healthcare innovation.

More Related Videos

Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

5.4K
Methylated DNA Immunoprecipitation
21:24

Methylated DNA Immunoprecipitation

Published on: January 2, 2009

24.3K

Related Experiment Videos

Last Updated: Mar 15, 2026

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
10:41

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

Published on: April 5, 2018

10.9K
Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

5.4K
Methylated DNA Immunoprecipitation
21:24

Methylated DNA Immunoprecipitation

Published on: January 2, 2009

24.3K

Area of Science:

  • Biomedical research and drug design
  • Epigenetics and gene expression regulation

Background:

  • Epigenetics influences gene expression by mediating environmental signals.
  • Understanding epigenetics is crucial for drug design and disease control.
  • Patent activity analysis offers insights into research trends and policy guidance.

Purpose of the Study:

  • To provide a comprehensive overview of epigenetics research and development.
  • To map the knowledge structure within the epigenetics patent landscape.

Main Methods:

  • Citation-based patent network analysis to visualize technological landscapes.
  • Identifying key patents for knowledge dissemination and bridging.
  • Topic modeling to highlight latent topics in patent documents.

Main Results:

  • Four main clusters identified in the patent network.
  • Clusters focus on histone deacetylase (HDAC) inhibition, DNA methylation, and computing/data mining for health.
  • DNA methylation inventions relate to epigenetic signaling for gene expression control.

Conclusions:

  • The field of epigenetic regulation mechanisms is in a growth phase.
  • Significant potential exists for healthcare improvement through understanding epigenetic modifications.
  • Interrelationships between epigenetic control and therapeutic compounds are key for future advancements.