Related Experiment Video

Updated: Mar 15, 2026

Enhancing Efficiency and Radiolabeling Yields of Carbon-11 Radioligands for Clinical Research Using the Loop Method
09:08

Enhancing Efficiency and Radiolabeling Yields of Carbon-11 Radioligands for Clinical Research Using the Loop Method

Published on: December 20, 2024

2.0K

The synthesis of tritium, carbon-14 and stable isotope labelled selective estrogen receptor degraders

Ryan A Bragg1, Nick Bushby2, Cecilia Ericsson3

  • 1Drug Safety & Metabolism, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridgeshire, UK. ryan.bragg@astrazeneca.com.

Journal of Labelled Compounds & Radiopharmaceuticals
|August 26, 2016
PubMed

Keywords:
carbon-14cyanationestrogen receptor degradertritium

More Related Videos

Screening for Phytoestrogens using a Cell-based Estrogen Receptor β Reporter Assay06:07

Screening for Phytoestrogens using a Cell-based Estrogen Receptor β Reporter Assay

Published on: June 7, 2020

5.4K
Preparation and Evaluation of 99mTc-labeled Tridentate Chelates for Pre-targeting Using Bioorthogonal Chemistry10:54

Preparation and Evaluation of 99mTc-labeled Tridentate Chelates for Pre-targeting Using Bioorthogonal Chemistry

Published on: February 4, 2017

8.7K

Related Concept Videos

Transducer Mechanism: Nuclear Receptors01:31

Transducer Mechanism: Nuclear Receptors

Nuclear receptors, or NRs, are unique transcription factors that regulate gene transcription and affect the cellular pathways involved in reproduction, development, or metabolism. Their ability to be stimulated by small lipophilic ligands and control vital cellular processes makes them ideal drug targets. Nearly 10-15% of currently prescribed drugs target these receptors.
About 48 different soluble family members of nuclear receptors are identified that can be divided into two main classes:
4.8K