Related Experiment Video
Updated: Mar 15, 2026

09:04
Generation of Self-assembled Vascularized Human Skin Equivalents
Published on: February 12, 2021
7.4K
Vitamin E in dermatology
Mohammad Abid Keen1, Iffat Hassan1
1Department of Dermatology, STD and Leprosy, Government Medical College and Associated SMHS Hospital, Srinagar, Jammu and Kashmir, India.
Indian Dermatology Online Journal
|August 26, 2016
Summary
Vitamin E, a fat-soluble antioxidant, offers skin protection against sun damage by scavenging free radicals. Further research is needed to establish clear dosages and clinical uses in dermatology.
Area of Science:
- Dermatology
- Cosmetic Science
- Antioxidant Research
Background:
- Vitamin E is a well-established fat-soluble antioxidant with over 50 years of dermatological use.
- It is a common ingredient in cosmetic products, valued for its protective qualities.
- Its primary mechanism involves acting as a free-radical scavenger to mitigate sun-induced skin damage.
Purpose of the Study:
- To review the cosmetic applications of Vitamin E in dermatology.
- To examine the clinical implications and potential therapeutic uses of Vitamin E.
- To highlight the need for evidence-based guidelines regarding Vitamin E's dermatological application.
Main Methods:
- Literature review of experimental studies on Vitamin E's effects.
- Analysis of existing research on photoprotective and antitumorigenic properties.
- Examination of current dermatological practices and product formulations.
Main Results:
- Experimental data suggests Vitamin E possesses photoprotective and antitumorigenic properties.
- Vitamin E's role as a free-radical scavenger protects skin from solar radiation.
- A lack of controlled clinical studies limits defined dosages and indications for dermatological use.
Conclusions:
- Vitamin E demonstrates significant potential in both cosmetic and clinical dermatology.
- Further controlled clinical trials are essential to validate its efficacy and establish precise usage guidelines.
- Optimizing Vitamin E's application in dermatology requires a better understanding of its therapeutic benefits and safety profile.
Related Concept Videos
Role of Skin in Vitamin D Synthesis
8.5K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
8.5K
Skin Diseases and Disorders
6.0K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.0K
Changes in Skin Color: Clinical Perspectives
4.1K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
4.1K
Vitamins
2.8K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
2.8K
Clinical Applications of Epidermal Stem Cells
3.4K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.4K
Reticular Dermis
5.4K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
5.4K

