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Updated: Jul 12, 2026
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A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
Published on: July 14, 2016
Genetics and senescence. I. Age-related changes in activity and exploration in three inbred strains of mice
1Laboratoire Génétique Neurogénétique et Comportement, URA 216 CNRS UER Biomédicale, Université Paris, France.
Physiology & Behavior
|March 1, 1989
Abstract:
Exploratory, locomotor and ambulatory activities were measured in nine independent groups of three inbred strains of mice (BALB/cBy, C57BL/6J and DBA/2J), at three different ages (150 days, 400 days and 750 days). The results show that for two of the three variables, the age-related changes present different patterns as a function of strain. The genetic and/or environmental correlates of the reactivity to aging may thus depend on the behavioral trait under study.
