Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

791
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
791
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

697
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
697
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

481
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
481
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

534
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
534
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

1.1K
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.1K
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

562
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
562

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Autophagy protein links ageing and Alzheimer disease.

Nature reviews. Neurology·2026
Same author

Veronique Miron: targeting neuroimmunology to protect myelin.

Nature reviews. Neurology·2026
Same author

Qiang Liu: addressing unmet clinical needs through neuroimmune mechanisms.

Nature reviews. Neurology·2026
Same author

Anne-Katrin Pröbstel: B cells, antibodies and microbiota in autoimmune disease.

Nature reviews. Neurology·2026
Same author

Lorenzo's House: shining a light on young-onset dementia.

Nature reviews. Neurology·2026
Same author

Targeting gut pathology is effective in an Alzheimer disease model.

Nature reviews. Neurology·2026

Related Experiment Video

Updated: Mar 15, 2026

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound
10:08

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound

Published on: December 2, 2014

16.6K

Stroke: Aortic stiffness predicts cognitive impairment

Ian Fyfe

    Nature Reviews. Neurology
    |August 27, 2016
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
    05:51

    Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

    Published on: May 3, 2018

    18.7K
    Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
    06:08

    Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging

    Published on: February 7, 2014

    17.8K

    Related Experiment Videos

    Last Updated: Mar 15, 2026

    Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound
    10:08

    Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound

    Published on: December 2, 2014

    16.6K
    Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
    05:51

    Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

    Published on: May 3, 2018

    18.7K
    Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
    06:08

    Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging

    Published on: February 7, 2014

    17.8K