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Urine Cytology: Collection, Film Preparation, and Evaluation
Linda M Vap1, Sarah B Shropshire2
1Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 300 West Drake Road, Fort Collins, CO 80523, USA.
The Veterinary Clinics of North America. Small Animal Practice
|August 27, 2016
Summary
Urine cytology is crucial for diagnosing animal urinary tract disease, differentiating inflammation, infection, and neoplasia. Proper sample collection and handling ensure accurate results for effective veterinary treatment.
Area of Science:
- Veterinary Pathology
- Diagnostic Cytology
Background:
- Cytologic examination of urine sediment aids in diagnosing urinary tract diseases in animals.
- Distinguishing inflammation, infection, and neoplasia is essential for appropriate treatment.
- Urine dipstick results for hemoglobin/blood require differentiation between hemorrhage and contamination.
Purpose of the Study:
- To highlight the importance of urine cytology in veterinary diagnostics.
- To emphasize the role of sample quality in diagnostic accuracy.
- To guide appropriate sample collection and handling for urinary tract cytology.
Main Methods:
- Cytologic examination of urine sediment.
- Evaluation of specimen collection and handling techniques.
- Correlation of cytologic findings with dipstick results.
Main Results:
- Urine cytology effectively distinguishes between inflammation, infection, and neoplasia.
- Specimen quality directly impacts result validity and interpretation.
- Sample collection method aids in localizing urinary tract pathology.
Conclusions:
- Cytologic examination of urine sediment is a valuable diagnostic tool for animals with suspected urinary tract disease.
- Proper specimen collection and handling are critical for accurate cytologic interpretation.
- Air-drying without heat fixation is recommended for urine cytology slides.
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