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Factors related to fatigue after paediatric acquired brain injury (ABI)
F van Markus-Doornbosch1, A J de Kloet1,2, M A M Berger2
1a Sophia Rehabilitation , The Hague , The Netherlands.
Insights
Children and youth experience significant fatigue after brain injuries, particularly non-traumatic brain injuries (NTBI). Older age and single-parent households are linked to increased fatigue levels in pediatric patients.
Area of Science:
- Pediatric Neurology
- Rehabilitation Medicine
- Child Psychology
Background:
- Acquired brain injury (ABI) in children and youth can lead to persistent symptoms, including fatigue.
- Understanding the prevalence and contributing factors of fatigue is crucial for effective management and rehabilitation.
Purpose of the Study:
- To evaluate the extent of fatigue in pediatric patients following traumatic brain injury (TBI) and non-traumatic brain injury (NTBI).
- To identify factors associated with increased fatigue levels in this population.
Main Methods:
- A follow-up study involving 88 children and youth (aged 4-20) diagnosed with ABI and their parents.
- The Paediatric Quality of Life Inventory™ Multidimensional Fatigue Scale (PedsQL™ MFS) was used to assess general, sleep/rest, and cognitive fatigue.
- Sociodemographic and disease characteristics were also collected.
Main Results:
- Two to three years post-diagnosis, parent-reported fatigue scores were considerable, especially after NTBI.
- Child-reported scores showed moderate correlation with parent-reported scores.
- Factors associated with higher fatigue included older age and single-parent household status.
Conclusions:
- Fatigue is a significant and persistent issue for children and youth after ABI, with notable levels reported by parents two years post-onset.
- Interventions should consider age and family structure as potential factors influencing fatigue severity.
Objective:
To assess the degree of fatigue in children and youth after traumatic and non-traumatic brain injury (TBI and NTBI) and related factors.
Method:
Follow-up study including patients with a hospital-based diagnosis of acquired brain injury (ABI), aged 4-20 years at onset and their parents. Parents and children (dependent on age) completed the Paediatric Quality of Life Inventory™ Multidimensional Fatigue Scale (PedsQL™ MFS), which measures general fatigue (GF), sleep/rest fatigue (SRF) and cognitive fatigue (CF). Additional assessments included the Child & Family Follow-up Survey (CFFS) and PedsQL™ 4.0 General Core Scales and sociodemographic and disease characteristics.
Results:
Eighty-eight parents completed the PedsQL™ MFS 24-30 months after diagnosis, with 49/88 patients (56%) completing the child version. The median age of the patients was 11 years (interquartile range [IQR] = 7). There were 69 patients with TBI (16% moderate/severe TBI) and 19 patients with NTBI (16% moderate/severe NTBI). The median parent-reported and child-reported PedsQL™ MFS Total Scale Scores were 76.5 (SD = 16.4) and 78.5 (12.9), respectively (Spearman r = 0.450, p = 0.001). Apart from NTBI, increasing age and a single-parent household were significantly associated with more fatigue according to the parent-reported PedsQL™ MFS Total Score (and/or one or more sub-scale scores).
Conclusion:
Two years after onset, in particular, the parent-reported fatigue after NTBI was considerable. Moreover, older children and children from a single-parent household were found to have higher fatigue levels.
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