Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

565
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
565
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

466
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
466
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

10.2K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
10.2K
Knee Joint01:23

Knee Joint

3.6K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
3.6K
Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

843
Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
843
Computed Tomography01:10

Computed Tomography

9.3K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
9.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Delayed transcallosal conduction to the lesioned sensorimotor cortex in multiple Sclerosis: A combined TMS 7 T-MRI study.

NeuroImage. Clinical·2026
Same author

Hyperintense FLAIR signal in the anterior cranial fossa.

Nature communications·2026
Same author

Measures of resting cartilage structure and composition in runners with and without knee osteoarthritis.

Osteoarthritis and cartilage open·2026
Same author

Repetitive transcranial magnetic stimulation to alleviate fatigue in multiple sclerosis-study protocol for a randomized sham-controlled double-blinded clinical trial.

Frontiers in neurology·2026
Same author

Longitudinal brain atrophy and mortality among people living in homelessness and precarious housing: A brief report of a longitudinal study.

PloS one·2026
Same author

C-DIR: Double Inversion Recovery with Controlled Artifact Suppression in Brain MRI.

AJNR. American journal of neuroradiology·2026

Related Experiment Video

Updated: Mar 15, 2026

In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
07:15

In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis

Published on: October 20, 2013

9.8K

Multi-echo GRE imaging of knee cartilage.

Joanna Yuen1,2,3, Jachin Hung3, Vanessa Wiggermann1,2,3

  • 1UBC MRI Research Centre, University of British Columbia, Vancouver, Canada.

Journal of Magnetic Resonance Imaging : JMRI
|August 27, 2016
PubMed
Summary

This study shows that 3D multi-echo gradient echo (GRE) magnetic resonance (MR) imaging can detect articular cartilage damage. Different MR contrasts effectively visualize chondral abnormalities, aiding in diagnosis.

Keywords:
chondral damagefrequencygradient echo

More Related Videos

Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis
07:06

Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis

Published on: July 6, 2022

6.1K
In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy
07:43

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy

Published on: July 2, 2021

3.7K

Related Experiment Videos

Last Updated: Mar 15, 2026

In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
07:15

In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis

Published on: October 20, 2013

9.8K
Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis
07:06

Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis

Published on: July 6, 2022

6.1K
In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy
07:43

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy

Published on: July 2, 2021

3.7K

Area of Science:

  • Radiology
  • Biomedical Imaging
  • Orthopedics

Background:

  • Articular cartilage health is crucial for joint function.
  • Accurate visualization of cartilage abnormalities is essential for diagnosis and treatment planning.
  • Current imaging techniques may have limitations in detecting early-stage cartilage damage.

Purpose of the Study:

  • To investigate the utility of 3D multi-echo gradient echo (GRE) magnetic resonance (MR) imaging for visualizing healthy and abnormal articular cartilage.
  • To assess the potential of using GRE signal magnitude, frequency, and T2* relaxation maps for cartilage imaging.

Main Methods:

  • Optimized 3D multi-echo GRE MR imaging parameters in healthy volunteers.
  • Acquired 3T MR images in four patients with suspected chondral damage before arthroscopic surgery.
  • Extracted average magnitude and frequency information, and generated T2* maps.
  • Correlated MR findings with arthroscopic grading (Outerbridge classification).

Main Results:

  • Outerbridge Grade I, II, and III cartilage damage were detectable using average magnitude and T2* maps.
  • Grade II and higher changes were also visible on MR frequency maps.
  • The study demonstrated the feasibility of using various imaging contrasts from the GRE sequence.

Conclusions:

  • 3D multi-echo GRE MR imaging is a feasible technique for visualizing articular cartilage abnormalities.
  • The combination of magnitude, frequency, and T2* relaxation maps provides valuable diagnostic information.
  • This imaging approach holds promise for improved detection and characterization of chondral damage.