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A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

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Breakthrough Cancer Pain: Ten Commandments.

Sebastiano Mercadante¹, Arturo Cuomo²

¹Anesthesia and Intensive Care and Pain Relief and Palliative Care Unit, La Maddalena Cancer Center, Palermo, Italy.

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research

|August 28, 2016

Summary

This review outlines 10 essential steps for diagnosing and treating breakthrough cancer pain (BTcP). Following these guidelines ensures accurate identification and personalized pharmacological management for cancer patients experiencing severe pain episodes.

Keywords:

breakthrough cancer pain cancer pain opioids

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Area of Science:

Oncology
Pain Management
Pharmacology

Background:

Breakthrough cancer pain (BTcP) is a significant challenge in cancer patient care.
Understanding BTcP phenomena and treatment has evolved over the past 25 years.
Effective management requires a structured diagnostic and treatment approach.

Purpose of the Study:

To establish 10 golden rules for the accurate diagnosis of BTcP.
To guide clinicians in developing personalized pharmacological treatment strategies for BTcP.
To improve the recognition and management of breakthrough cancer pain.

Main Methods:

Critical review of existing literature on breakthrough cancer pain.
Synthesis of key principles into a 10-commandment framework.
Focus on diagnostic pathway and pharmacotherapy selection.

Main Results:

The 10 commandments cover assessment of background analgesia, drug selection, BTcP characteristics, diagnosis, continuous evaluation, tailored treatment, medication selection, dosing, and patient education.
These steps provide a comprehensive roadmap for clinicians.
Adequate recognition and treatment of BTcP can be achieved through systematic application.

Conclusions:

A structured, 10-step approach facilitates accurate BTcP diagnosis.
Personalized pharmacological treatment is crucial for effective BTcP management.
Clinician education and adherence to guidelines improve patient outcomes in breakthrough cancer pain.