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The Whole (Cell) Is Less Than the Sum of Its Parts
Jonathan G Van Vranken1, Jared Rutter2
1Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.
Cell
|August 28, 2016
Abstract:
Despite advances in metabolite profiling, a full picture of the metabolic landscape of the cell has been limited by sub-cellular compartmentalization, which segregates distinct nutrient pools into membrane-bound organelles. Now, Chen et al. describe methods for overcoming this hurdle and provide a new quantitative picture of the mitochondrial metabolome.
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