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Pooja Patel1, Hearns W Charles1, James Park2

  • 1Division of Vascular and Interventional Radiology, Department of Radiology, New York University Medical Center, 660 First Ave., 7th Floor, New York, NY 10016.

Journal of Vascular and Interventional Radiology : JVIR
|August 28, 2016
PubMed
Abstract

No abstract available in PubMed .

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Chronic liver disease significantly impacts drug metabolism due to alterations in hepatic blood flow and enzyme accessibility. This disruption affects the body's pharmacokinetics—the movement and processing of drugs within the system. Key enzymes crucial for metabolizing medications become less accessible, changing how drugs are processed and utilized. Furthermore, liver disease influences the synthesis of plasma proteins, such as albumin and globulins, which play critical roles in drug...
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