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Updated: Mar 15, 2026
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Published on: December 3, 2017
Concomitant Multiple Joint Arthroplasty Infections: Report on 16 Cases.
Valérie Zeller1, Delphine Dedome2, Luc Lhotellier3
1Service de Chirurgie Osseuse et Traumatologique, Groupe Hospitalier Diaconesses Croix Saint-Simon, Paris, France; Centre de Référence des Infections Ostéo-Articulaires Complexes, Groupe Hospitalier Diaconesses Croix Saint-Simon, Paris, France; Service de Médecine Interne et Rhumatologie, Groupe Hospitalier Diaconesses Croix Saint-Simon, Paris, France.
Multiple prosthetic joint infections are rare but serious, often stemming from staphylococcal or streptococcal bacteremia. Treatment requires a multidisciplinary approach, with surgical intervention and antibiotic therapy showing good outcomes.
Area of Science:
- Orthopedics
- Infectious Diseases
- Surgical Infections
Background:
- Concomitant multiple prosthetic joint infections are rare, serious events.
- These infections present significant medical and surgical therapeutic challenges.
- Understanding their characteristics is crucial for effective management.
Purpose of the Study:
- To describe the epidemiologic, clinical, and microbiological features of concomitant multiple joint arthroplasty infections.
- To detail the treatment strategies employed for these complex cases.
- To report the outcomes of patients with multiple prosthetic joint infections.
Main Methods:
- Retrospective, single-center cohort study (January 2000 - January 2014).
- Inclusion criteria: patients with at least two concomitant, microbiologically documented prosthetic joint infections during the same septic episode.
- Data collected on patient demographics, infection characteristics, treatment, and outcomes.
Main Results:
- Sixteen patients were included, with a median age of 78 years.
- Hematogenous contamination was the primary route, often associated with Staphylococcus aureus or Streptococcus species.
- Curative strategies included synovectomies and 1-stage exchange arthroplasties, with a low reinfection rate (1/11 patients).
Conclusions:
- Concomitant prosthetic joint infections frequently occur during staphylococcal or streptococcal bacteremia.
- Effective treatment necessitates a case-by-case discussion by a multidisciplinary team.
- Individualized treatment plans are essential for managing these challenging infections.
