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Open Aortic Arch Reconstruction After Coronary Artery Bypass Surgery: Worth the Effort?
Eduard Quintana1, Pietro Bajona2, Hartzell V Schaff3
1Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota; Cardiovascular Surgery Department, Hospital Clínic de Barcelona, Institut Clínic Cardiovascular, University of Barcelona Medical School, Barcelona, Spain.
Insights
Open aortic arch surgery after coronary artery bypass grafting (CABG) is high-risk. This study found acceptable early and midterm outcomes, with low stroke risk, highlighting perfusion strategies and myocardial protection as key to success.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Surgery
Background:
- Open aortic arch surgery following coronary artery bypass grafting (CABG) presents significant risks.
- Establishing the risk profile for this specific patient cohort is crucial for surgical planning.
Purpose of the Study:
- To review the surgical approach and outcomes of open aortic arch surgery in patients with prior CABG.
- To identify risk factors and predictors of mortality in this high-risk patient population.
Main Methods:
- A retrospective review of 650 patients undergoing aortic arch surgery with circulatory arrest between 2000-2014.
- Analysis of 45 patients (7%) with previous CABG, including preoperative coronary angiograms and myocardial protection management.
Main Results:
- The mean interval from CABG to aortic arch surgery was 6.8 years.
- Indications included aneurysms (44%), valvular disease (11%), and acute aortic dissection (22%).
- Perioperative mortality was 13% with a 2.2% stroke rate. Age and nonuse of retrograde cardioplegia predicted early mortality. Survival at 1, 3, and 5 years was 74%, 65%, and 52%, respectively.
Conclusions:
- Aortic arch surgery after prior CABG can be performed with acceptable early and midterm results.
- Perfusion strategies and myocardial protection methods significantly influence successful outcomes.
- While intermediate survival is lower than the general population, the procedure offers a low stroke risk.
Abstract:
Open aortic arch surgery after coronary artery bypass grafting (CABG) is considered a high-risk operation. We reviewed our surgical approach and outcomes to establish the risk profile for this patient population. In methods, from 2000-2014, 650 patients underwent aortic arch surgery with circulatory arrest. Of these, 45 (7%) had previous CABG. Complete medical record was available for review including all preoperative coronary angiograms and detailed management of myocardial protection. In results, the mean interval from previous CABG to aortic arch surgery was 6.8 ± 7.1 years. At reoperation, 33 (73%) patients had hemiarch replacement and 12 (27%) had a total arch replacement. The following were the indications for surgery: fusiform aneurysm in 20 (44%), pseudoaneurysm in 6 (13%), endocarditis in 4 (9%), valvular disease in 5 (11%), and acute aortic dissection in 10 (22%). There were 6 perioperative deaths (13%) and 1 stroke (2.2%). Selective antegrade cerebral perfusion was used in 13 patients (28.9%) and retrograde perfusion in 6 (13.3%). Survival was 74%, 65%, and 52% at 1, 3, and 5-year follow-up, respectively. Only predictors of early mortality were age (odds ratio = 1.20, CI: 1.01-1.44; P = 0.04) and nonuse of retrograde cardioplegia for myocardial protection (odds ratio = 6.80, CI: 1.06-43.48; P = 0.04). Intermediate survival of these patients was significantly lower than those of a sex-matched and age-matched population (P < 0.001). In conclusion, aortic arch surgery after previous CABG can be performed with acceptable early and midterm results and low risk of stroke. Perfusion strategies and myocardial protection contribute to successful outcomes.
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