Natural Compounds A Weapon to Ameliorate Breast Cancer Cells: A Review

Area of Science:

• Oncology
• Pharmacology
• Natural Products Chemistry

Background:

• Breast cancer is a major global health concern for women, characterized by cellular signaling pathway disruptions.
• Genetic variability necessitates personalized treatment approaches for breast cancer.
• Identifying novel therapeutic targets and lead compounds is crucial for effective breast cancer management.

Purpose of the Study:

• To review the pathological aspects of breast cancer.
• To examine the effects of natural compounds on breast cancer cells.
• To elucidate the potential mechanisms of action for these natural compounds.

Main Methods:

• Comprehensive literature search of PubMed, Science Direct, Web of Knowledge, Scopus, and Google Scholar.
• Analysis of studies on breast cancer pathology and signaling pathways.
• Review of research on plant-derived secondary metabolites and their bioactivity against cancer cells.

Main Results:

• Natural compounds, rich in secondary metabolites, show significant potential as bioactive molecules against breast cancer.
• Evidence suggests plant-derived compounds can modulate key signaling pathways involved in breast cancer cell apoptosis.
• Various natural compounds exhibit cytotoxic effects on different breast cancer cell lines.

Conclusions:

• Natural compounds represent a promising avenue for developing novel breast cancer therapies.
• Targeting specific signaling pathways with plant-derived molecules may facilitate personalized treatment strategies.
• Further research into the mechanisms of action of natural compounds is warranted for drug development.