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Related Concept Videos

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

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Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
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Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

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Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
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Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
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Personality Disorders: Dependent and Obsessive-Compulsive01:24

Personality Disorders: Dependent and Obsessive-Compulsive

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Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
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Disorders of the Nervous Tissue01:28

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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
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Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

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Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
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Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
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Anxiety: Overview01:18

Anxiety: Overview

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Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
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Related Experiment Video

Updated: Mar 15, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
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Soft Neurological Signs and Cognitive Function in Obsessive-compulsive Disorder Patients.

Chetali Vijay Dhuri1, Shubhangi R Parkar1

  • 1Department of Psychiatry, Seth G. S. Medical College and KEM Hospital, Mumbai, Maharashtra, India.

Indian Journal of Psychological Medicine
|August 30, 2016
PubMed
Summary
This summary is machine-generated.

Obsessive-compulsive disorder (OCD) is linked to biological factors, specifically soft neurological signs and cognitive deficits. This study found these neurobiological markers are significantly more prevalent in OCD patients compared to controls.

Keywords:
Cognitive functionneurological soft signsobsessive-compulsive disorder

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Historically, psychoanalytical theories dominated obsessive-compulsive disorder (OCD) research.
  • Modern research increasingly points to biological underpinnings of OCD.

Purpose of the Study:

  • To investigate neurobiological markers, specifically soft neurological signs (NSS) and cognitive functions, in individuals with OCD.
  • To explore the role of these biological factors in the development of OCD.

Main Methods:

  • A cross-sectional study was conducted with 50 OCD patients and age/education-matched controls.
  • Neurological soft signs (NSS) and cognitive deficits were assessed using established instruments.

Main Results:

  • OCD patients exhibited significantly more NSS across various domains, including motor coordination, sensory integration, and spatial orientation.
  • Cognitive deficits were more pronounced in OCD patients in areas such as visuospatial ability, executive function, attention, and working memory.

Conclusions:

  • The study underscores the significant role of biological factors, including soft neurological signs and cognitive dysfunction, in the etiology of OCD.
  • These findings support a neurobiological model for understanding obsessive-compulsive disorder.