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Primary CNS vasculitis presenting as intraventricular bleeding.

Sreeja Hareendranathan Pillai¹, Sapna Erat Sreedharan¹, Girish Menon²

¹Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.

Annals of Indian Academy of Neurology

|August 30, 2016

Summary

Primary angiitis of the central nervous system (PACNS) can cause rare intraventricular hemorrhages. This case highlights secondary aneurysms as a cause of bleeding in PACNS progression.

Keywords:

Infarcts intraventricular hemorrhage primary angiitis of the central nervous system (PACNS)

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Last Updated: Mar 15, 2026

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Area of Science:

Neurology
Vascular Neurology
Neuroimmunology

Background:

Primary angiitis of the central nervous system (PACNS) is a rare inflammatory condition affecting CNS blood vessels.
While PACNS primarily impacts medium and small arteries, its association with intracranial hemorrhages is less frequently documented.

Observation:

This report details a specific case of PACNS.
The patient presented with intraventricular hemorrhage, a less common manifestation of the disease.

Findings:

The intraventricular hemorrhage in this PACNS case was attributed to the development of aneurysms.
These aneurysms were a direct consequence of the ongoing vasculitis and its progression.

Implications:

This case expands the understanding of potential hemorrhagic complications in PACNS.
Recognizing secondary aneurysms as a cause of intraventricular hemorrhage is crucial for timely diagnosis and management of PACNS.