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Updated: Mar 15, 2026

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
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HIF1α and metabolic reprogramming in inflammation

Sarah E Corcoran, Luke A J O'Neill

    The Journal of Clinical Investigation
    |August 30, 2016
    PubMed
    Summary

    Hypoxia-inducible factor 1-alpha (HIF1α) reprograms immune cell metabolism, enhancing their function and inflammatory responses. It is crucial for T cell activation and dendritic cell maturation, promoting inflammation.

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