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Published on: June 6, 2020
Brief Report: Cesarean Delivery and Subsequent Fecundability
Rose G Radin1, Ellen M Mikkelsen, Kenneth J Rothman
1From the aDepartment of Epidemiology, Boston University School of Public Health, Boston, MA; bEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, Bethesda, MD; cDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; dRTI Health Solutions, Research Triangle Park, NC; and eDepartment of Obstetrics and Gynecology, Boston University School of Medicine, Boston, MA.
Cesarean delivery may impact future fertility. Planned cesarean delivery or cesarean delivery for breech presentation was linked to reduced subsequent fecundability in women after their first birth.
Area of Science:
- Reproductive Health
- Obstetrics
- Perinatal Epidemiology
Background:
- Cesarean delivery is linked to fewer subsequent births, but reasons are unclear.
- Previous studies did not fully account for pregnancy intention or surgical indications.
- This study investigates cesarean delivery's impact on subsequent fecundability.
Purpose of the Study:
- To evaluate the association between cesarean delivery and subsequent fecundability.
- To analyze how delivery type and fetal presentation affect fertility after childbirth.
Main Methods:
- Cohort study of 910 primiparous Danish women (2007-2012).
- Obstetrical history from registry linkage; time-to-pregnancy via questionnaire.
- Fecundability ratios (FRs) adjusted for confounders.
Main Results:
- Emergency cesarean delivery (cephalic presentation) showed no significant impact on fecundability (FR = 1.0).
- Cesarean delivery for breech presentation reduced fecundability (FR = 0.72).
- Planned cesarean delivery (cephalic presentation) significantly reduced fecundability (FR = 0.51).
Conclusions:
- The association between cesarean delivery and subsequent fecundability depends on fetal presentation and delivery circumstances.
- Breech presentation and planned cesarean delivery are associated with lower fertility for subsequent pregnancies.
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