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High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
Published on: November 15, 2013
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Isabel Higuera Pulgar1, Irene Bretón Lesmes, María Luisa Carrascal Fabián
1Unidad de Nutrición Clínica y Dietética. Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón. Madrid. ihiguera@salud.madrid.org.
Nutricion Hospitalaria
|August 31, 2016
Summary
The six-food group elimination diet (SFED) for eosinophilic esophagitis (EoE) may lead to nutritional deficiencies in energy, protein, fiber, and key micronutrients. Regular nutritional status assessment and supplementation are crucial for patients with EoE on SFED.
Area of Science:
- Gastroenterology
- Allergy and Immunology
- Nutritional Science
Background:
- Eosinophilic esophagitis (EoE) is a chronic, emerging immunoallergic disease in adults, triggered by food antigens.
- It causes recurrent esophageal dysfunction and inflammation, requiring individualized treatment.
- Dietary management, including empirical food elimination, is a key therapeutic approach.
Purpose of the Study:
- To evaluate the dietary intake of eosinophilic esophagitis patients on a six-food group elimination diet (SFED).
- To identify potential nutritional deficiencies associated with the SFED in this patient group.
Main Methods:
- A descriptive cross-sectional study was conducted with 14 EoE patients undergoing SFED treatment.
- Dietary intake was assessed using a 72-hour food record.
- Statistical analysis compared intake with Spanish healthy adult references using Mann-Whitney, Kruskal-Wallis, and Chi-squared tests (p < 0.05).
Main Results:
- Patients on the SFED showed deficiencies in energy, protein, and fiber intake.
- A significant portion (60%) of the sample did not meet recommended intake for calcium, zinc, magnesium, folic acid, niacin, and vitamins B2 and D.
- These deficiencies were assessed considering age and sex.
Conclusions:
- The SFED approach for EoE requires careful consideration of potential nutritional shortfalls.
- Periodic nutritional status assessment, including micronutrient evaluation, is essential for patients on this diet.
- A specific supplementation plan should accompany the SFED to address identified deficiencies.

