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Related Concept Videos

Vagina01:26

Vagina

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The vaginal canal is a tubular structure averaging about 10 cm in length that acts as the entryway to the female reproductive system and the passageway for menstrual flow and childbirth. The interior walls of the vagina exhibit concentric folds called rugae and are topped by an area known as the fornix, which connects with the protruding cervical portion of the uterus. This canal is comprised of an external fibrous layer, a muscular middle layer, and an inner lining with mucosal rugae, which...
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Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

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The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
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Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
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Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

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Uterus and Cervix01:18

Uterus and Cervix

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The uterus, commonly called the womb, is a vital reproductive organ in females designed to provide a nurturing environment for the implantation and growth of an embryo. It is shaped like a hollow pear and positioned between the urinary bladder and the rectum. The uterus's structure allows it to support and protect a developing fetus throughout pregnancy.
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs...
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External Female Genitals01:15

External Female Genitals

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The vulva encompasses the external structures of the female reproductive system. At the forefront is the monpubis, a cushion of fatty tissue atop the pubic bone. Once puberty sets in, this area typically grows hair. Extending from just behind the mons pubis are the labia majora (labia = 'lips'; majora = 'larger'), which are larger skin fs olds coated with hair. Nestled within are the labia minora (labia = 'lips'; minora = 'smaller'), which are thinner, more...
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TRPS1 Reliably Stains Benign and Malignant Lesions Arising Within Vulvar Anogenital Mammary-like Glands.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists·2025
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Related Experiment Video

Updated: Mar 15, 2026

Author Spotlight: A Reproductive Hysteroscopy Approach for Complete Endometrial Polyp Removal and Enhanced Endometrial Receptivity
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Author Spotlight: A Reproductive Hysteroscopy Approach for Complete Endometrial Polyp Removal and Enhanced Endometrial Receptivity

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Pseudosarcomatous Vaginal Polyp.

Alexis Heller1, Adanna Ukazu2, Qing Wang2

  • 11 Columbia University, New York, NY, USA.

International Journal of Surgical Pathology
|August 31, 2016
PubMed
Summary

Vaginal fibroepithelial polyps, though rare in pregnancy, can mimic malignancy due to atypical cells. Accurate diagnosis is crucial to avoid misclassifying these benign lesions.

Area of Science:

  • Gynecologic Pathology
  • Reproductive Endocrinology

Background:

  • Fibroepithelial polyps are rare vaginal tumors, often hormonally influenced.
  • These lesions can occur in the lower female genital tract.
  • Histological atypia and hypercellularity can lead to misdiagnosis as malignancy.

Observation:

  • A case report details a 31-year-old woman presenting with a vaginal polyp postpartum.
  • The polyp exhibited hypercellular stroma with atypical cells.

Findings:

  • Histopathological examination revealed atypical cells within the polyp's stroma.
  • The observed features mimicked malignant characteristics.

Implications:

  • Accurate differentiation between benign polyps and malignant lesions is critical.
Keywords:
differentialgenital neoplasmspathology; diagnosispolyps

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  • Avoid misclassifying benign vaginal fibroepithelial polyps as cancerous based on atypical features.