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The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

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Published on: June 30, 2014

Pediatric multiple sclerosis: Cognition and mood.

Maria Pia Amato¹, Lauren B Krupp², Leigh E Charvet²

¹From Department NEUROFARBA (M.P.A.), Section Neurosciences, University of Florence, Italy; Department of Neurology (L.B.K., L.E.C.), Stony Brook Medicine, NY; Cognitive Psychology and Methodology and Division of Paediatric Neurology and Developmental Medicine (I.P.), University Children's Hospital Basel, Switzerland; and Department of Psychology (C.T.), York University, Canada. mariapia.amato@unifi.it.

|August 31, 2016

Summary

This summary is machine-generated.

Cognitive and mood issues in pediatric-onset multiple sclerosis (POMS) are understudied. Research is growing to understand these challenges in children and adolescents with POMS.

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Area of Science:

Neuroscience
Pediatric Neurology
Clinical Psychology

Background:

Limited research exists on cognitive functioning in pediatric-onset multiple sclerosis (POMS) compared to adults.
POMS presents unique challenges due to disease onset during critical brain development, myelination, and neural network maturation.
Cognitive impacts in POMS cannot be directly extrapolated from adult studies.

Purpose of the Study:

To summarize current knowledge on cognitive and mood-related difficulties in POMS.
To identify gaps in understanding and establish priorities for future research in POMS.
To characterize the neuropsychological patterns and functional consequences of POMS.

Main Methods:

Review of existing literature and clinical series on POMS.
Increased focus on systematic research in specialized MS centers over the last decade.
Assessment of cognitive impairments and mood-related difficulties in POMS patients.

Main Results:

Cognitive functioning and mood disturbances are growing concerns in the POMS population.
Systematic research is emerging to assess prevalence and characterize POMS-related difficulties.
Understanding the specific neuropsychological profile of POMS is a key research objective.

Conclusions:

Further systematic research is crucial to fully understand and address cognitive and mood issues in POMS.
Future studies should focus on characterizing the unique impact of POMS on developing cognitive faculties.
Identifying functional consequences and research priorities is essential for improving POMS care.