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Related Concept Videos

Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

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The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
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Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
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Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
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Spinal Cord01:26

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The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
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Spinal Cord: Cross-sectional Anatomy01:16

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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
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The Spinal Cord01:54

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The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
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Related Experiment Video

Updated: Mar 15, 2026

Spinal Cord Electrophysiology
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Spinal sensory circuits in motion.

Urs Lucas Böhm1, Claire Wyart1

  • 1Institut du Cerveau et de la Moelle Épinière, Campus Hospitalier Pitié-Salpêtrière, 47 bld de l'Hôpital, 75013 Paris, France; UPMC Univ., Paris 06, France; Inserm UMR S1127, France; CNRS UMR 7225, France.

Current Opinion in Neurobiology
|August 31, 2016
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Summary

Sensory neurons within the spinal cord relay information from cerebrospinal fluid to motor circuits, influencing locomotion. This finding challenges traditional views of sensory feedback in spinal cord injury recovery.

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Area of Science:

  • Neuroscience
  • Motor Control
  • Spinal Cord Research

Background:

  • The role of sensory feedback in locomotion has been extensively debated.
  • Proprioceptive pathways in spinal circuits are crucial for motor control.
  • Peripheral mechanosensation mechanisms have been identified for modulating locomotion.

Purpose of the Study:

  • To investigate the role of novel sensory feedback pathways in locomotion.
  • To challenge the traditional view of sensory input originating solely from the periphery.
  • To explore the contribution of spinal cord sensory neurons to locomotion and recovery after injury.

Main Methods:

  • Utilized advanced genetics and behavior analysis.
  • Employed optogenetics to probe neural circuits.
  • Combined quantitative analysis of behavior with genetic manipulation.

Main Results:

  • Identified GABAergic sensory neurons within the spinal cord.
  • Demonstrated these neurons relay mechanical and chemical information from cerebrospinal fluid.
  • Showcased the modulation of motor circuits by these novel sensory pathways.

Conclusions:

  • Spinal cord sensory neurons represent a significant, previously underappreciated feedback pathway.
  • These findings offer new insights into locomotion control and potential therapeutic targets for spinal cord injury.
  • The study highlights the importance of exploring non-traditional sensory pathways in the nervous system.