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Updated: Mar 15, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
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Crizotinib: from discovery to accelerated development to front-line treatment

F Blackhall1, F Cappuzzo2

  • 1Christie NHS Foundation Trust, Institute of Cancer Sciences, University of Manchester, Manchester, UK fiona.blackhall@christie.nhs.uk.

Annals of Oncology : Official Journal of the European Society for Medical Oncology
|August 31, 2016
PubMed
Summary

Crizotinib offers a new treatment for ALK-positive non-small-cell lung cancer (NSCLC). This targeted therapy improves survival and quality of life for patients with advanced NSCLC.

Keywords:
anaplastic lymphoma kinasecrizotinibnon-small-cell lung cancer

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