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Updated: Mar 15, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
Consensus opinion of US neurologists on practice patterns in RIS, CIS, and RRMS: Evolution of treatment practices
Carlo Tornatore1, J Theodore Phillips1, Omar Khan1
1Medstar Georgetown University Hospital (CT), Washington, DC; Baylor Institute for Immunology Research (JTP), Dallas, TX; Wayne State University School of Medicine (OK), Detroit, MI; Icahn School of Medicine at Mount Sinai (AEM), New York, NY; and Infusion Communications (MH), Haddam, CT.
Purpose Of Review:
To assess current practice patterns of US neurologists in patients with radiologically isolated syndrome (RIS), clinically isolated syndrome (CIS), and relapsing-remitting multiple sclerosis (RRMS) using case-based Web surveys.
Recent Findings:
We identified a total of 47 points of consensus (≥75% agreement) with regard to diagnosis, treatment, and monitoring of RIS, CIS, and RRMS. Current US treatment consensus patterns emphasize (1) MRI in multiple sclerosis (MS) diagnosis and subsequent treatment decisions, (2) treatment of early disease, (3) aggressive initial treatment of highly active MS, and (4) close patient monitoring for clinical response and adverse effects of disease-modifying drugs.
Summary:
These findings may offer insights into harmonizing MS care and represent the first steps in potentially establishing a more uniform approach to the treatment of patients with MS in the United States without compromising the need for individual treatment for each patient.

