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Hepatocellular carcinoma in elderly patients: challenges and solutions
Angélique Brunot1, Samuel Le Sourd1, Marc Pracht1
1Department of Medical Oncology, Centre Eugene Marquis, Rennes, France.
Hepatocellular carcinoma (HCC) incidence is rising in the elderly. Fit elderly patients can receive standard HCC treatments, while unfit patients require multidisciplinary care.
Area of Science:
- Oncology
- Geriatrics
- Hepatology
Background:
- Hepatocellular carcinoma (HCC) is a leading cause of cancer death globally.
- Increasing incidence of HCC in the elderly due to delayed development in hepatitis C and nonalcoholic fatty liver disease.
- HCC in older adults presents a growing global health challenge.
Purpose of the Study:
- To review the literature on managing hepatocellular carcinoma in elderly patients.
- To emphasize the importance of geriatric assessment in treatment decisions for elderly HCC patients.
- To support tailored treatment strategies based on fitness for elderly HCC patients.
Main Methods:
- Literature review of studies on hepatocellular carcinoma in the elderly.
- Inclusion of geriatric screening tools like Geriatric-8 and Vulnerable Elders Survey-13.
- Emphasis on comprehensive geriatric assessment for treatment selection.
Main Results:
- Elderly patients selected as fit can undergo the same treatment options as younger patients.
- Unfit elderly patients require management by a multidisciplinary team of oncologists and geriatricians.
- The review supports an oncogeriatric approach for elderly HCC patients.
Conclusions:
- Proper oncogeriatric assessment is crucial for determining treatment for elderly HCC patients.
- Standard treatments are viable for fit elderly individuals.
- Multidisciplinary care is essential for unfit elderly patients with HCC.
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